climbazole
Sign in to saveClimbazole is a topical antifungal agent commonly used in the treatment of human fungal skin infections such as dandruff, seborrhoeic dermatitis and eczema. Climbazole has shown a high in vitro and in vivo efficacy against Malassezia spp. that appear to play an important role in the pathogenesis of dandruff. Its chemical structure and properties are similar to other azole fungicides such as ketoconazole, clotrimazole and miconazole. __TOC__
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 292.098
Show 3 more facts
- chemical formula
- C₁₅H₁₇ClN₂O₂
- canonical SMILES
- CC(C)(C)C(=O)C(N1C=CN=C1)OC2=CC=C(C=C2)Cl
- Commons category
- Climbazole
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Encyclopedic overview
4 sectionsContents
- Indications and formulations
- Side effects
- See also
- References
Climbazole is a topical antifungal agent commonly used in the treatment of human fungal skin infections such as dandruff, seborrhoeic dermatitis and eczema. Climbazole has shown a high in vitro and in vivo efficacy against Malassezia spp. that appear to play an important role in the pathogenesis of dandruff. Its chemical structure and properties are similar to other azole fungicides such as ketoconazole, clotrimazole and miconazole. __TOC__
==Indications and formulations== It is most commonly found as an active ingredient in OTC anti-dandruff and anti-fungal products, including shampoos, lotions and conditioners. It may be accompanied by other active ingredients such as zinc pyrithione or triclosan.
Excerpted from Wikipedia’s “climbazole” article, available under the CC BY-SA 4.0 licence.
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