clioquinol
Sign in to saveAlso known as Domeform-HC, Quin-O-Creme, Vioform, Chloroiodoquin, 5-chloro-7-iodoquinolin-8-ol, Iodochloroxyquinoline, Iodochlorhydroxyquin, 7-Iodo-5-chloroxine
Clioquinol (iodochlorhydroxyquin) tradename Entero-Vioform is an antifungal drug and antiprotozoal drug. It is neurotoxic in large doses. It is a member of a family of drugs called hydroxyquinolines which inhibit certain enzymes related to DNA replication. The drugs have been found to have activity against both viral and protozoal infections.
Research
1,294 papers- Clioquinol: To harm or heal.Pharmacology & therapeutics · 2019
- Feasibility of Repurposing Clioquinol for Cancer Therapy.Recent patents on anti-cancer drug discovery · 2020
- The toxicology of Clioquinol.Toxicology letters · 2008
- Clioquinol for the treatment of Alzheimer's Disease.The Cochrane database of systematic reviews · 2006
- Antimicrobial activity of clioquinol and nitroxoline: a scoping review.Archives of microbiology · 2022
via PubMed
~5 min read
Encyclopedic overview
8 sectionsContents
- Antiprotozoal use
- Subacute myelo-optic neuropathy
- Topical use
- Potential use as a preventive or treatment in prostate cancer
- Use in neurodegenerative diseases
- Continued use and manufacture around the world
- See also
- References
Clioquinol (iodochlorhydroxyquin) tradename Entero-Vioform is an antifungal drug and antiprotozoal drug. It is neurotoxic in large doses. It is a member of a family of drugs called hydroxyquinolines which inhibit certain enzymes related to DNA replication. The drugs have been found to have activity against both viral and protozoal infections.
==Antiprotozoal use==
Excerpted from Wikipedia’s “clioquinol” article, available under the CC BY-SA 4.0 licence.
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