COG7
Sign in to saveAlso known as CDG2E, component of oligomeric golgi complex 7
Conserved oligomeric Golgi complex subunit 7 is a protein that in humans is encoded by the COG7 gene.
Gene data
COG7- Name
- component of oligomeric golgi complex 7
- Type
- protein-coding
- Aliases
- CDG2E
The protein encoded by this gene resides in the golgi, and constitutes one of the 8 subunits of the conserved oligomeric Golgi (COG) complex, which is required for normal golgi morphology and localization. Mutations in this gene are associated with the congenital disorder of glycosylation type IIe.[provided by RefSeq, May 2010].
via MyGene.info
Gene · Ensembl
component of oligomeric golgi complex 7
- Symbol
- COG7
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:23,388,493-23,453,210
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 33431
- genomic start
- 23388493
- exact match
- identifiers.org/ncbigene/91949
- genomic end
- 23453189
- cytogenetic location
- 16p12.2
Sources (4)
via Wikidata · CC0
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Article
4 sectionsContents
- Interactions
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- External links
Conserved oligomeric Golgi complex subunit 7 is a protein that in humans is encoded by the COG7 gene.
Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG7 (Ungar et al., 2002).[supplied by OMIM]