HOXB7

Also known as HHO.C1, HOX2, HOX2C, Hox-2.3, homeobox B7

Homeobox protein Hox-B7 is a protein that in humans is encoded by the HOXB7 gene.

In the Vinony graph

Within Vinony's link graph, HOXB7 is referenced by 813 other articles, and connects out to Q180686, human chromosome 17 and homeobox.

Vinony files it under Genes on human chromosome 17 and Transcription factors.

Its subject is documented across 6 Wikipedia language editions.

Gene data

HOXB7

Name: homeobox B7
Type: protein-coding
Position: 48,607,222–48,633,572 (−)
Aliases: HHO.C1, HOX2, HOX2C, Hox-2.3
Ensembl: ENSG00000260027
RefSeq RNA: NM_004502.4
RefSeq protein: NP_004493.3

This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma. [provided by RefSeq, Jul 2008].

Gene Ontology

Biological process

regulation of DNA-templated transcription regulation of DNA-templated transcription regulation of transcription by RNA polymerase II anterior/posterior pattern specification positive regulation of transcription by RNA polymerase II embryonic organ development positive regulation of branching involved in ureteric bud morphogenesis

Molecular function

RNA polymerase II cis-regulatory region sequence-specific DNA binding RNA polymerase II cis-regulatory region sequence-specific DNA binding DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific DNA-binding transcription activator activity, RNA polymerase II-specific DNA binding DNA-binding transcription factor activity

Cellular component

chromatin nucleus nucleus nucleus nucleoplasm nuclear body

via MyGene.info

Gene · Ensembl

homeobox B7

Symbol: HOXB7
Biotype: Protein coding
Organism: Homo sapiens
Location: 17:48,607,222-48,633,572
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein HOXB7 PDB 1ahd.png

Show 5 more facts

HomoloGene ID: 55828
exact match: identifiers.org/ncbigene/3217
genomic end: 46710934
genomic start: 48607232
cytogenetic location: 17q21.32

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

6 sections

Contents

Function
Interactions
See also
References
Further reading
External links

Homeobox protein Hox-B7 is a protein that in humans is encoded by the HOXB7 gene.

== Function == This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma.

Excerpted from Wikipedia’s “HOXB7” article, available under the CC BY-SA 4.0 licence.