CPE

Also known as CPH, carboxypeptidase E, IDDHH, BDVS

protein-coding gene in the species Homo sapiens

Gene data

CPE

Name: carboxypeptidase E
Type: protein-coding
Aliases: BDVS, CPH, IDDHH

This gene encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. This protein may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in this gene are implicated in type 2 diabetes. [provided by RefSeq, Nov 2015].

via MyGene.info