CTSG
Sign in to saveAlso known as CATG, CG, cathepsin G
protein-coding gene in the species Homo sapiens
Gene data
CTSG- Name
- cathepsin G
- Type
- protein-coding
- Position
- 24,573,518–24,576,250 (−)
- Aliases
- CATG, CG
- Ensembl
- ENSG00000100448
- RefSeq RNA
- NM_001911.3, XM_011536499.2, XM_054375488.1
- RefSeq protein
- NP_001902.1, XP_011534801.1, XP_054231463.1
The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Sep 2014].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
cathepsin G
- Symbol
- CTSG
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:24,573,518-24,576,250
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein CTSG PDB 1au8.png
Show 5 more facts
- HomoloGene ID
- 105646
- exact match
- identifiers.org/ncbigene/1511
- genomic end
- 24576250
- genomic start
- 24573518
- cytogenetic location
- 14q12
via Wikidata · CC0