C1S

Name

complement C1s

Type

protein-coding

Position

6,988,259–7,071,281 (+)

Aliases

EDSPD2

Ensembl

ENSG00000182326

RefSeq RNA

NM_001346850.2, NM_001734.5, NM_201442.4, XM_054373117.1

RefSeq protein

NP_001333779.1, NP_001725.1, NP_958850.1, XP_054229092.1

This gene encodes a serine protease, which is a major constituent of the human complement subcomponent C1. C1s associates with two other complement components C1r and C1q in order to yield the first component of the serum complement system. Defects in this gene are the cause of selective C1s deficiency. [provided by RefSeq, Mar 2009].