Carboxypeptidase B2
Sign in to saveAlso known as CPB2, thrombin-activable fibrinolysis inhibitor, Carboxypeptidase U, CPU, TAFI, carboxypeptidase B2 (plasma, carboxypeptidase U), carboxypeptidase R
mammalian protein found in Homo sapiens
In the Vinony graph
Within Vinony's link graph, Carboxypeptidase B2 is referenced by 69 other articles, and connects out to blood coagulation, Coagulation factor II, thrombin and PubMed.
It is catalogued under topics including Fibrinolytic system and Genes on human chromosome 13.
Its subject is documented across 7 Wikipedia language editions.
Protein · UniProt
Carboxypeptidase B2
- Gene
- CPB2
- Organism
- Homo sapiens (Human)
- Length
- 423 aa
- Molecular mass
- 48,424 Da
- Evidence
- 1: Evidence at protein level
Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down-regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin
Swiss-Prot (reviewed) · via UniProt
Clinical Trials
1 registered- PHASE3RECRUITINGStudy of the Long-term Effects of P2Y12 Inhibitor Monotherapy and Coagulation Markers After Percutaneous Coronary Angioplasty.Cardiocentro Ticino · NCT07582835
Wikidata facts
- Instance of
- protein
Show 3 more facts
- cell component
- extracellular exosome
- biological process
- fibrinolysis
- found in taxon
- Homo sapiens
Sources (3)
via Wikidata · CC0