SERPINF2
Sign in to saveAlso known as A2AP, AAP, ALPHA-2-PI, API, PLI, serpin family F member 2, alpha2AP
protein-coding gene in the species Homo sapiens
Gene data
SERPINF2- Name
- serpin family F member 2
- Type
- protein-coding
- Aliases
- A2AP, AAP, ALPHA-2-PI, API, PLI, alpha2AP
This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].
via MyGene.info
Gene · Ensembl
serpin family F member 2
- Symbol
- SERPINF2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 17:1,742,069-1,755,271
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- 2R9Y.png
Show 6 more facts
- HomoloGene ID
- 719
- genomic start
- 1646130
- exact match
- identifiers.org/ncbigene/5345
- genomic end
- 1755265
- cytogenetic location
- 17p13.3
- Commons category
- Alpha 2-antiplasmin
Sources (6)
via Wikidata · CC0
Connections
blood coagulation
Entity
Coagulation factor II, thrombin
Protein
Q180686
Entity
N-terminus
Entity
plasmin
Protein
Serpin family A member 1
Medication
Ensembl genome database project
Entity
serpin
Entity
SERPINB3
Gene
International Standard Book Number
Entity
enzyme
Entity
Wikidata
Entity
myocardial infarction
Entity
stroke
Entity
chromosome
Entity
digital object identifier
Entity
International Standard Serial Number
Entity
liver cirrhosis
Entity
antibody
Entity
blood plasma
Entity