CSTA
Sign in to saveAlso known as AREI, STF1, STFA, Cystatin A, PSS4
protein-coding gene in the species Homo sapiens
Gene data
CSTA- Name
- cystatin A
- Type
- protein-coding
- Position
- 122,325,248–122,341,969 (+)
- Aliases
- AREI, PSS4, STF1, STFA
- Ensembl
- ENSG00000121552
- RefSeq RNA
- NM_005213.4
- RefSeq protein
- NP_005204.1
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
cystatin A
- Symbol
- CSTA
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:122,325,238-122,359,856
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- 3kse.png
Show 5 more facts
- HomoloGene ID
- 3819
- exact match
- identifiers.org/ncbigene/1475
- genomic end
- 122341969
- genomic start
- 122325248
- cytogenetic location
- 3q21.1
Sources (4)
via Wikidata · CC0