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GeneQ17911029· pop 6· linked from 6 articles

CSTF1

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Also known as CstF-50, CstFp50, cleavage stimulation factor subunit 1

Cleavage stimulation factor 50 kDa subunit is a protein that in humans is encoded by the CSTF1 gene.

Gene data

CSTF1
Name
cleavage stimulation factor subunit 1
Type
protein-coding
Position
56,392,368–56,406,362 (+)
Aliases
CstF-50, CstFp50
Ensembl
ENSG00000101138
RefSeq RNA
NM_001033521.2, NM_001033522.2, NM_001324.3, XM_011528600.2, XM_054323070.1
RefSeq protein
NP_001028693.1, NP_001028694.1, NP_001315.1, XP_011526902.1, XP_054179045.1

This gene encodes one of three subunits which combine to form cleavage stimulation factor (CSTF). CSTF is involved in the polyadenylation and 3'end cleavage of pre-mRNAs. Similar to mammalian G protein beta subunits, this protein contains transducin-like repeats. Several transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008].

Gene Ontology

Molecular function

RNA bindingprotein binding

Pathways

mRNA surveillance pathway - Homo sapiens (human)DiseaseInfectious diseasemRNA 3'-end processingProcessing of Capped Intron-Containing Pre-mRNARNA Polymerase II Transcription TerminationRNA Polymerase II TranscriptionGene expression (Transcription)Processing of Capped Intronless Pre-mRNAProcessing of Intronless Pre-mRNAs

via MyGene.info

Gene · Ensembl

cleavage stimulation factor subunit 1

Symbol
CSTF1
Biotype
Protein coding
Organism
Homo sapiens
Location
20:56,392,368-56,406,362
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 7 more facts
HomoloGene ID
1012
found in taxon
Homo sapiens
exact match
identifiers.org/ncbigene/1477
genomic end
56406362
genomic start
54967427
chromosome
human chromosome 20
cytogenetic location
20q13.2-q13.31
Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

4 sections
Contents
  • Interactions
  • References
  • External links
  • Further reading

Cleavage stimulation factor 50 kDa subunit is a protein that in humans is encoded by the CSTF1 gene.

This gene encodes one of three subunits which combine to form cleavage stimulation factor (CSTF). CSTF is involved in the polyadenylation and 3' end cleavage of pre-mRNAs. Similar to mammalian G protein beta subunits, this protein contains transducin-like repeats. Several transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.

Excerpted from Wikipedia’s “CSTF1” article, available under the CC BY-SA 4.0 licence.

Available in 5 languages

via Wikidata sitelinks · CC0