cyclodextrin
Sign in to saveAlso known as cyclodextrines, cycloamyloses, cyclodextrins
thumb|upright=2.0|Chemical structure of the three main types of cyclodextrins. Cyclodextrins are a family of cyclic oligosaccharides, consisting of a macrocyclic ring of glucose subunits joined by α-1,4 glycosidic bonds. Cyclodextrins are produced from starch by enzymatic conversion. They are used in food, pharmaceutical, drug delivery, and chemical industries, as well as agriculture and environmental engineering.
Research
30,885 papers- γ-Cyclodextrin.International journal of pharmaceutics · 2017
- Drug-Encapsulated Cyclodextrin Nanosponges.Methods in molecular biology (Clifton, N.J.) · 2021
- Cyclodextrin-Based Nanosystems as Drug Carriers for Cancer Therapy.Anti-cancer agents in medicinal chemistry · 2020
- Amphiphilic cyclodextrin nanoparticles.International journal of pharmaceutics · 2017
- Cyclodextrin Complexes for the Treatment of Chagas Disease: A Literature Review.International journal of molecular sciences · 2024
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Article
11 sectionsContents
- Applications
- Drug delivery
- Chromatography
- Other
- Structure
- Synthesis
- Derivatives
- Research
- History
- Safety
- References
thumb|upright=2.0|Chemical structure of the three main types of cyclodextrins. Cyclodextrins are a family of cyclic oligosaccharides, consisting of a macrocyclic ring of glucose subunits joined by α-1,4 glycosidic bonds. Cyclodextrins are produced from starch by enzymatic conversion. They are used in food, pharmaceutical, drug delivery, and chemical industries, as well as agriculture and environmental engineering.
Cyclodextrins are composed of 5 or more α-D-glucopyranoside units linked 1 → 4, as in amylose (a fragment of starch). Typical cyclodextrins contain a number of glucose monomers ranging from six to eight units in a ring, creating a cone shape: α (alpha)-cyclodextrin: 6 glucose subunits β (beta)-cyclodextrin: 7 glucose subunits γ (gamma)-cyclodextrin: 8 glucose subunits