Structure via PubChem · Public domain (PubChem)
dicycloplatin
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- Formula
- C12H20N2O8Pt
- Molecular weight
- 515.38 g/mol
- IUPAC name
- azane;cyclobutane-1,1-dicarboxylate;cyclobutane-1,1-dicarboxylic acid;platinum(2+)
- SMILES
- C1CC(C1)(C(=O)O)C(=O)O.C1CC(C1)(C(=O)[O-])C(=O)[O-].N.N.[Pt+2]
- InChIKey
- IIJQICKYWPGJDT-UHFFFAOYSA-L
- Polar surface area
- 157 Ų
- H-bond donors
- 4
- H-bond acceptors
- 10
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- coordination complex
- Mass
- 515.087
- Has use
- medication
Show 2 more facts
- chemical formula
- C₁₂H₂₀N₂O₈Pt
- canonical SMILES
- C1CC(C1)(C(=O)O)C(=O)O.C1CC(C1)(C(=O)[O-])C(=O)[O-].N.N.[Pt+2]
Sources (2)
via Wikidata · CC0
~4 min read
Encyclopedic overview
5 sectionsContents
- Medical uses
- Side effects
- Chemical structure
- Mechanism of action
- Notes
Dicycloplatin is a chemotherapy medication used to treat a number of cancers which includes the non-small-cell lung carcinoma and prostate cancer.
Some side effects which are observed from the treatment by dicycloplatin are nausea, vomiting, thrombocytopenia, neutropenia, anemia, fatigue, loss of appetite, liver enzyme elevation and alopecia. The drug is a platinum-based antineoplastic, and it works by causing mitochondrial dysfunction which leads to cell death.
Excerpted from Wikipedia’s “dicycloplatin” article, available under the CC BY-SA 4.0 licence.