DLGAP1
Sign in to saveAlso known as DAP-1, DAP-1-ALPHA, DAP-1-BETA, DAP1, DLGAP1A, DLGAP1B, GKAP, SAPAP1
Disks large-associated protein 1 (DAP-1), also known as guanylate kinase-associated protein (GKAP), is a protein that in humans is encoded by the DLGAP1 gene. DAP-1 is known to be highly enriched in synaptosomal preparations of the brain, and present in the post-synaptic density.
Gene data
DLGAP1- Name
- DLG associated protein 1
- Type
- protein-coding
- Position
- 3,494,443–4,455,307 (−)
- Aliases
- DAP-1, DAP-1-ALPHA, DAP-1-BETA, DAP1, DLGAP1A, DLGAP1B, GKAP, SAPAP1
- Ensembl
- ENSG00000170579
- RefSeq RNA
- NM_001003809.3, NM_001242761.2, NM_001242762.2, NM_001242763.2, NM_001242764.2
- RefSeq protein
- NP_001003809.1, NP_001229690.1, NP_001229691.1, NP_001229692.1, NP_001229693.1
Predicted to enable molecular adaptor activity. Predicted to be a structural constituent of postsynaptic density. Predicted to be involved in several processes, including aggresome assembly; regulation of postsynaptic neurotransmitter receptor activity; and regulation of proteasomal protein catabolic process. Predicted to be located in plasma membrane. Predicted to be part of postsynaptic density. Predicted to be active in glutamatergic synapse and postsynaptic density, intracellular component. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Biological process
Pathways
via MyGene.info
Gene · Ensembl
DLG associated protein 1
- Symbol
- DLGAP1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 18:3,494,443-4,455,307
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 31258
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9229
- genomic end
- 4455307
- genomic start
- 3496030
- chromosome
- human chromosome 18
- cytogenetic location
- 18p11.31
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Disks large-associated protein 1 (DAP-1), also known as guanylate kinase-associated protein (GKAP), is a protein that in humans is encoded by the DLGAP1 gene. DAP-1 is known to be highly enriched in synaptosomal preparations of the brain, and present in the post-synaptic density.
== Function ==
Excerpted from Wikipedia’s “DLGAP1” article, available under the CC BY-SA 4.0 licence.