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GeneQ18050948· pop 6· linked from 274 articles

DYNLL2

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Also known as DNCL1B, Dlc2, RSPH22, dynein light chain LC8-type 2

Dynein light chain 2, cytoplasmic is a protein that in humans is encoded by the DYNLL2 gene.

Gene data

DYNLL2

Name: dynein light chain LC8-type 2
Type: protein-coding
Position: 58,082,863–58,095,542 (+)
Aliases: DNCL1B, Dlc2, RSPH22
Ensembl: ENSG00000264364
RefSeq RNA: NM_080677.3
RefSeq protein: NP_542408.1

Predicted to enable dynein intermediate chain binding activity and dynein light intermediate chain binding activity. Predicted to be involved in cilium assembly. Located in 9+0 non-motile cilium and centrosome. Is active in glutamatergic synapse and postsynapse. [provided by Alliance of Genome Resources, Apr 2022]

Gene Ontology

Biological process

cilium movement microtubule-based process flagellated sperm motility positive regulation of intracellular transport intraciliary retrograde transport positive regulation of mitotic cell cycle spindle assembly checkpoint

Molecular function

protein binding identical protein binding protein-containing complex binding dynein intermediate chain binding scaffold protein binding

Cellular component

male germ cell nucleus nucleus centrosome cytosol cytoskeleton cytoskeleton cytoplasmic dynein complex cytoplasmic dynein complex

Pathways

Vasopressin-regulated water reabsorption - Homo sapiens (human)Salmonella infection - Homo sapiens (human)Apoptosis Intrinsic Pathway for Apoptosis Activation of BH3-only proteins Adaptive Immune System Activation of BMF and translocation to mitochondria Amplification of signal from the kinetochores Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Signal Transduction

via MyGene.info

Gene · Ensembl

dynein light chain LC8-type 2

Symbol: DYNLL2
Biotype: Protein coding
Organism: Homo sapiens
Location: 17:58,082,825-58,095,542
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein DYNLL2 PDB 1cmi.png

Show 5 more facts

exact match: identifiers.org/ncbigene/140735
HomoloGene ID: 115597
genomic end: 58095542
genomic start: 58083419
cytogenetic location: 17q22

Sources (4)

via Wikidata · CC0

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Article

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Contents

Interactions
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Further reading
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External links

Dynein light chain 2, cytoplasmic is a protein that in humans is encoded by the DYNLL2 gene.

== Interactions ==

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via Wikidata sitelinks · CC0

Categories

Genes on human chromosome 17