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enpiprazole

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EntityQ5379478· pop 5· linked from 154 articles

enpiprazole

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Enpiprazole (INN, BAN) is an anxiolytic drug of the phenylpiperazine group that was never marketed. It produces anxiolytic-like effects in animals, though these effects appear to be biphasic and may reverse at high doses. It is known to produce ortho-chlorophenylpiperazine (oCPP) as a metabolite.

Chemical data

Formula
C16H21ClN4
Molecular weight
304.82 g/mol
IUPAC name
1-(2-chlorophenyl)-4-[2-(1-methylpyrazol-4-yl)ethyl]piperazine
SMILES
CN1C=C(C=N1)CCN2CCN(CC2)C3=CC=CC=C3Cl
InChIKey
WBFVWQJVMMIQFI-UHFFFAOYSA-N
XLogP
2.8
Polar surface area
24.3 Ų
H-bond donors
0
H-bond acceptors
3
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
304.145
Show 2 more facts
chemical formula
C₁₆H₂₁ClN₄
canonical SMILES
CN1C=C(C=N1)CCN2CCN(CC2)C3=CC=CC=C3Cl
Sources (2)

via Wikidata · CC0

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Encyclopedic overview

2 sections
Contents
  • See also
  • References

Enpiprazole (INN, BAN) is an anxiolytic drug of the phenylpiperazine group that was never marketed. It produces anxiolytic-like effects in animals, though these effects appear to be biphasic and may reverse at high doses. It is known to produce ortho-chlorophenylpiperazine (oCPP) as a metabolite.

==See also== Acaprazine Enciprazine Lorpiprazole Mepiprazole Tolpiprazole

Excerpted from Wikipedia’s “enpiprazole” article, available under the CC BY-SA 4.0 licence.

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