buclizine
Sign in to saveAlso known as UCB-4445, 1-(p-tert-Butylbenzyl)-4-(4-chloro-alpha-phenylbenzyl)piperazine
Buclizine is an antihistamine and anticholinergic of the diphenylmethylpiperazine group. It is considered to be an antiemetic, similar to meclizine.
Research
52 papers- Buclizine.Profiles of drug substances, excipients, and related methodology · 2011
- Buclizine crystal forms: First Structural Determinations, counter-ion stoichiometry, hydration, and physicochemical properties of pharmaceutical relevance.International journal of pharmaceutics · 2020
- Buclizine, a new tranquilizing agent.Journal of the American Geriatrics Society · 1959
- Teratogenic effect of buclizine and hydroxyzine in the rat and chlorcyclizine in the mouse.American journal of obstetrics and gynecology · 1966
- Buclizine is back again! This time as a pediatric appetite stimulant.Indian journal of pharmacology · 2011
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 432.233227
- Has use
- medication
Show 7 more facts
- chemical formula
- C₂₈H₃₃ClN₂
- medical condition treated
- vomiting
- subject has role
- histamine antagonist
- canonical SMILES
- CC(C)(C)C1=CC=C(C=C1)CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl
- World Health Organisation international non-proprietary name
- buclizine
- defined daily dose
- 50
- Commons category
- Buclizine
Sources (3)
via Wikidata · CC0
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Encyclopedic overview
1 sectionsContents
- References
Buclizine is an antihistamine and anticholinergic of the diphenylmethylpiperazine group. It is considered to be an antiemetic, similar to meclizine.
In the United Kingdom, buclizine is one of three drugs contained in Migraleve tablets, marketed by McNeil Healthcare for migraines.
Excerpted from Wikipedia’s “buclizine” article, available under the CC BY-SA 4.0 licence.