EPC1

Also known as Epl1, enhancer of polycomb homolog 1

Enhancer of polycomb homolog 1 is a protein that in humans is encoded by the EPC1 gene.

Gene data

EPC1

Name: enhancer of polycomb 1
Type: protein-coding
Position: 32,267,751–32,378,798 (−)
Aliases: Epl1
Ensembl: ENSG00000120616
RefSeq RNA: NM_001272004.3, NM_001272019.4, NM_001282391.3, NM_001382753.1, NM_001382754.1
RefSeq protein: NP_001258933.1, NP_001258948.1, NP_001269320.1, NP_001369682.1, NP_001369683.1

This gene encodes a member of the polycomb group (PcG) family. The encoded protein is a component of the NuA4 histone acetyltransferase complex and can act as both a transcriptional activator and repressor. The encoded protein has been linked to apoptosis, DNA repair, skeletal muscle differentiation, gene silencing, and adult T-cell leukemia/lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012].