eperisone

Also known as (2RS)-1-(4-ethylphenyl)-2-methyl-3-(1-piperidyl)propan-1-one, Eperisonum, Eperison, Eperisona, Epérisone

Eperisone (formulated as the eperisone hydrochloride salt) is an antispasmodic drug.

Key facts

Drug.Verifiedfields: changed
Drug.Watchedfields: changed
Drug.verifiedrevid: 477167014
Drug.IUPAC_name: (2RS)-1-(4-Ethylphenyl)-2-methyl-3-(1-piperidyl)propan-1-one
Drug.image: Eperisone.png
Drug.image_class: skin-invert-image
Drug.image2: Eperisone3d.png
Drug.image_class2: bg-transparent
Drug.tradename: Myonal
Drug.legal_status: Rx-only
Drug.routes_of_administration: Oral
Drug.index2_label: HCl
Drug.CAS_number: 64840-90-0
Drug.CAS_number2: 56839-43-1
Drug.UNII: 2M2P0551D3
Drug.UNII2: U38O8U7P6X
Drug.ATC_prefix: M03
Drug.ATC_suffix: BX09

via Wikipedia infobox

Chemical data

Formula: C17H25NO
Molecular weight: 259.4 g/mol
IUPAC name: 1-(4-ethylphenyl)-2-methyl-3-piperidin-1-ylpropan-1-one

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 3
Molecule type: Small molecule
Indications: Back pain, Low back pain

via ChEMBL · EBI

Research

129 papers

Eperisone-induced immediate hypersensitivity reactions.The Korean journal of internal medicine · 2026
Eperisone-Induced Anaphylaxis: Pharmacovigilance Data and Results of Allergy Testing.Allergy, asthma & immunology research · 2019
Clinical characteristics of eperisone-induced immediate-type hypersensitivity.Asian Pacific journal of allergy and immunology · 2020
Eperisone Hydrochloride, a Muscle Relaxant, Is a Potent P2X7 Receptor Antagonist.Chemical & pharmaceutical bulletin · 2024
Pharmacokinetics of eperisone following oral administration in healthy Korean volunteers.Biopharmaceutics & drug disposition · 2021

via PubMed

Wikidata facts

Mass: 259.194

Show 4 more facts

chemical formula: C₁₇H₂₅NO
canonical SMILES: CCC1=CC=C(C=C1)C(=O)C(C)CN2CCCCC2
defined daily dose: 0.15
Commons category: Eperisone

Sources (3)

via Wikidata · CC0

~6 min read

Article

15 sections

Contents

Indications
Presentation
Dosage and administration
Safety during pregnancy and breast-feeding
Pharmacology
Contraindications
Cautions
Side effects
Drug interactions
Safety in overdose
Future developments
Brand names
See also
References
Further reading

Eperisone (formulated as the eperisone hydrochloride salt) is an antispasmodic drug.

Eperisone acts by relaxing both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and suppression of the pain reflex. The drug inhibits the vicious circle of myotonia by decreasing pain, ischaemia, and hypertonia in skeletal muscles, thus alleviating stiffness and spasticity, and facilitating muscle movement