ERC1
Sign in to saveAlso known as Cast2, ELKS, ERC-1, RAB6IP2, ELKS/RAB6-interacting/CAST family member 1
ELKS/RAB6-interacting/CAST family member 1 is a protein that in humans is encoded by the ERC1 gene. The name ELKS is derived from "protein rich in the amino acids E, L, K and S"
In the Vinony graph
Within Vinony's link graph, ERC1 is referenced by 5 other articles, and connects out to PubMed, human chromosome 12 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 12.
Its subject is documented across 5 Wikipedia language editions.
Gene data
ERC1- Name
- ELKS/RAB6-interacting/CAST family member 1
- Type
- protein-coding
- Aliases
- Cast2, ELKS, ERC-1, RAB6IP2
The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014].
via MyGene.info
Gene · Ensembl
ELKS/RAB6-interacting/CAST family member 1
- Symbol
- ERC1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:989,998-1,495,933
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 14229
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/23085
- chromosome
- human chromosome 12
- genomic start
- 1099675
- genomic end
- 1605099
- cytogenetic location
- 12p13.33
- expressed in
- corpus callosum
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
ELKS/RAB6-interacting/CAST family member 1 is a protein that in humans is encoded by the ERC1 gene. The name ELKS is derived from "protein rich in the amino acids E, L, K and S"
The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13). Multiple transcript variants encoding different isoforms have been found for this gene. ELKS has been reported to direct vesicles with RAB6A to melanosomes.
Excerpted from Wikipedia’s “ERC1” article, available under the CC BY-SA 4.0 licence.