ethotoin
Sign in to saveAlso known as Peganone®, 3-ethyl-5-phenyl-2,4-imidazolidinedione, 1-ethyl-2,5-dioxo-4-phenylimidazolidine, 3-ethyl-5-phenylhydantoin, (+-)-3-ethyl-5-phenylhydantoin, 3-ethyl-5-phenylimidazolidin-2,4-dione, 1-Ethyl-2,5-dioxo-4-phenylimidazolidine, 3-Ethyl-5-phenyl-2,4-imidazolidinedione
Ethotoin (previously marketed as Peganone) is an anticonvulsant drug used in the treatment of epilepsy. It is a hydantoin, similar to phenytoin. It is not available in the United States.
Research
48 papers- Nonlinear ethotoin kinetics.Clinical pharmacology and therapeutics · 1983
- ETHOTOIN.Journal of the American Medical Association · 1958
- Dose-dependent kinetics of ethotoin in man.Clinical and experimental pharmacology & physiology · 1975
- Ethotoin in seizures of childhood and adolescence.Neurology · 1984
- Enantioselective pharmacokinetics of ethotoin in humans following single oral doses of the racemate.Chirality · 1992
via PubMed
Wikidata facts
- Mass
- 204.09
Show 5 more facts
- chemical formula
- C₁₁H₁₂N₂O₂
- World Health Organisation international non-proprietary name
- ethotoin
- canonical SMILES
- CCN1C(=O)C(NC1=O)C2=CC=CC=C2
- defined daily dose
- 2.5
- Commons category
- Ethotoin
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Article
7 sectionsContents
- Mechanism of action
- Approval history
- Indications and usage
- Dosing
- Side effects
- Chemistry
- References
Ethotoin (previously marketed as Peganone) is an anticonvulsant drug used in the treatment of epilepsy. It is a hydantoin, similar to phenytoin. It is not available in the United States.
==Mechanism of action== The mechanism of action of ethotoin is similar to that of phenytoin.