ethylphenidate

Also known as EPH

Ethylphenidate (EPH) is a central nervous system (CNS) stimulant and a close analog of methylphenidate.

Key facts

Drug.Verifiedfields: changed
Drug.Watchedfields: changed
Drug.verifiedrevid: 432850456
Drug.IUPAC_name: (RS)-Ethyl 2-phenyl-2-piperidin-2-ylacetate
Drug.image: Ethylphenidate.svg
Drug.image_class: skin-invert-image
Drug.width: 225px
Drug.image2: Ethylphenidate-3D-ball-model.png
Drug.image_class2: bg-transparent
Drug.legal_AU: S8 (Controlled Drug)
Drug.legal_BR: F2
Drug.legal_CA: Schedule 3
Drug.legal_UK: Class B
Drug.legal_UK_comment: Temporary Class Drug
Drug.legal_DE: Anlage II
Drug.legal_UN: P II
Drug.routes_of_administration: By mouth, insufflation, inhalation, sublingual, rectal, intramuscular, intravenous
Drug.bioavailability: Variable

via Wikipedia infobox

Research

60 papers

Ethylphenidate as a selective dopaminergic agonist and methylphenidate-ethanol transesterification biomarker.Journal of pharmaceutical sciences · 2014
Ethylphenidate: availability, patterns of use, and acute effects of this novel psychoactive substance.European journal of clinical pharmacology · 2015
Metabolomics of Methylphenidate and Ethylphenidate: Implications in Pharmacological and Toxicological Effects.European journal of drug metabolism and pharmacokinetics · 2017
Seven fatalities associated with ethylphenidate.Forensic science international · 2016
L- and D-threo ethylphenidate concentrations, pharmacokinetics, and pharmacodynamics in horses.Drug testing and analysis · 2018

via PubMed

Wikidata facts

Mass: 247.157

Show 3 more facts

chemical formula: C₁₅H₂₁NO₂
canonical SMILES: CCOC(=O)C(C1CCCCN1)C2=CC=CC=C2
Commons category: Ethylphenidate

Sources (2)

via Wikidata · CC0

~6 min read

Article

6 sections

Contents

Pharmacology
Pharmacokinetics
Pharmacodynamics
Legality
See also
References

Ethylphenidate (EPH) is a central nervous system (CNS) stimulant and a close analog of methylphenidate.

Ethylphenidate acts as a norepinephrine–dopamine reuptake inhibitor, meaning it effectively boosts the levels of the norepinephrine and dopamine neurotransmitters in the brain, by binding to, and partially blocking the transporter proteins that normally remove those monoamines from the synaptic cleft.