etonogestrel
Sign in to saveAlso known as 3-keto-desogestrel, Implanon®, Nexplanon®, ORG-3236, 3-Oxodesogestrel, 3-Ketodesogestrel, étonogestrel, Etonogestrelum
Etonogestrel is a medication which is used as a means of birth control for women. It is available as an implant placed under the skin of the upper arm under the brand names Nexplanon and Implanon. It is a progestin that is also used in combination with ethinylestradiol, an estrogen, as a vaginal ring under the brand names NuvaRing and Circlet. Etonogestrel is effective as a means of birth control and lasts at least three or four years with some data showing effectiveness for five years. Following removal, fertility quickly returns.
Key facts
- Drug.Verifiedfields
- verified
- Drug.Watchedfields
- verified
- Drug.verifiedrevid
- 461098012
- Drug.IUPAC_name
- (8S,9S,10R,13S,14S,17R)-13-Ethyl-17-ethynyl-17-hydroxy-11-methylidene-2,6,7,8,9,10,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
- Drug.image
- Etonogestrel.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 225
- Drug.image2
- Etonogestrel molecule ball.png
- Drug.image_class2
- bg-transparent
- Drug.width2
- 235
- Drug.tradename
- Circlet, Implanon, Nexplanon, others
- Drug.MedlinePlus
- a604032
- Drug.pregnancy_AU
- B3
- Drug.routes_of_administration
- Subcutaneous implant, vaginal ring
- Drug.class
- Progestogen; Progestin
- Drug.ATC_prefix
- G03
- Drug.ATC_suffix
- AC08
- Drug.legal_AU
- S4
via Wikipedia infobox
Research
1,140 papers- A systematic review on clinical effectiveness, side-effect profile and meta-analysis on continuation rate of etonogestrel contraceptive implant.Reproductive health · 2021
- Etonogestrel implant effectiveness.Canadian family physician Medecin de famille canadien · 2022
- Etonogestrel Subdermal Implant-Associated Regression of Endometrial Intraepithelial Neoplasia.Obstetrics and gynecology · 2019
- Etonogestrel-releasing subdermal contraceptive implant: Budget impact analysis based on the Brazilian private healthcare system.PloS one · 2024
- Management of Etonogestrel implant migration into the pulmonary artery.Contraception · 2022
via PubMed
~17 min read
Encyclopedic overview
23 sectionsContents
- Medical uses
- Side effects
- Overdose
- Interactions
- Device description
- Insertion and removal
- Fertility after removal
- Differences
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- Synthesis
- History
- Society and culture
- Generic names
- Brand names
- Availability
- Research
- See also
- References
- Further reading
- External links
Etonogestrel is a medication which is used as a means of birth control for women. It is available as an implant placed under the skin of the upper arm under the brand names Nexplanon and Implanon. It is a progestin that is also used in combination with ethinylestradiol, an estrogen, as a vaginal ring under the brand names NuvaRing and Circlet. Etonogestrel is effective as a means of birth control and lasts at least three or four years with some data showing effectiveness for five years. Following removal, fertility quickly returns.
Side effects of etonogestrel include menstrual irregularities, breast tenderness, mood changes, acne, headaches, vaginitis, and others. Etonogestrel is a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. It works by stopping ovulation, thickening the mucus around the opening of the cervix, and altering the lining of the uterus. It has very weak androgenic and glucocorticoid activity and no other important hormonal activity.
Excerpted from Wikipedia’s “etonogestrel” article, available under the CC BY-SA 4.0 licence.