Structure via PubChem · Public domain (PubChem)
fenoverine
Sign in to saveFenoverine (INN) is an antispasmodic [also known as spasmolytics] drug, which acts by inhibiting calcium channels [much in the same way as traditional calcium channel blockers, which are used as antianginal drugs]. In the case of Fenoverine, the relaxation occurs in abdominal / intestinal smooth muscles, while in case of antianginal drugs, the relaxation occurs in coronary vessels. Notably Fenoverine does not act as an antianginal agent. ==Toxicity== Fenoverine is known to cause rhabdomyolysis. ==References==
Chemical data
- Formula
- C26H25N3O3S
- Molecular weight
- 459.6 g/mol
- IUPAC name
- 2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-1-phenothiazin-10-ylethanone
- SMILES
- C1CN(CCN1CC2=CC3=C(C=C2)OCO3)CC(=O)N4C5=CC=CC=C5SC6=CC=CC=C64
- InChIKey
- UBAJTZKNDCEGKL-UHFFFAOYSA-N
- XLogP
- 4.2
- Polar surface area
- 70.6 Ų
- H-bond donors
- 0
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- gastrointestinal disease
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 459.162
Show 3 more facts
- canonical SMILES
- C1CN(CCN1CC2=CC3=C(C=C2)OCO3)CC(=O)N4C5=CC=CC=C5SC6=CC=CC=C64
- chemical formula
- C₂₆H₂₅N₃O₃S
- subject has role
- parasympatholytic
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- Toxicity
- References
Fenoverine (INN) is an antispasmodic [also known as spasmolytics] drug, which acts by inhibiting calcium channels [much in the same way as traditional calcium channel blockers, which are used as antianginal drugs]. In the case of Fenoverine, the relaxation occurs in abdominal / intestinal smooth muscles, while in case of antianginal drugs, the relaxation occurs in coronary vessels. Notably Fenoverine does not act as an antianginal agent. ==Toxicity== Fenoverine is known to cause rhabdomyolysis. ==References==
Category:Phenothiazines Category:Carboxamides Category:Piperazines Category:Benzodioxoles
Excerpted from Wikipedia’s “fenoverine” article, available under the CC BY-SA 4.0 licence.