Structure via PubChem · Public domain (PubChem)
fluralaner
Sign in to saveFluralaner (INN), sold under the brand name Bravecto among others, is a systemic insecticide and acaricide that is administered orally or topically.
Chemical data
- Formula
- C22H17Cl2F6N3O3
- Molecular weight
- 556.3 g/mol
- IUPAC name
- 4-[5-(3,5-dichlorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-2-methyl-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]benzamide
via PubChem
Wikidata facts
- Mass
- 555.055
Show 3 more facts
- canonical SMILES
- CC1=C(C=CC(=C1)C2=NOC(C2)(C3=CC(=CC(=C3)Cl)Cl)C(F)(F)F)C(=O)NCC(=O)NCC(F)(F)F
- chemical formula
- C₂₂H₁₇Cl₂F₆N₃O₃
- Commons category
- Fluralaner
Sources (2)
via Wikidata · CC0
~2 min read
Article
5 sectionsContents
- Mode of action
- Society and culture
- Legal status
- Research
- References
Fluralaner (INN), sold under the brand name Bravecto among others, is a systemic insecticide and acaricide that is administered orally or topically.
==Mode of action== Fluralaner inhibits γ-aminobutyric acid (GABA)-gated chloride channels (GABA receptors) and L-glutamate-gated chloride channels (GluCls). Potency of fluralaner is comparable to fipronil (a related GABA-antagonist insecticide and acaricide).
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Categories
BenzamidesCat medicationsChemical pages without DrugBank identifierChloroarenesConvulsantsDog medicationsDrugs developed by Merck & Co.Drugs with non-standard legal statusECHA InfoCard ID from WikidataGABAA receptor negative allosteric modulatorsInsecticidesIsoxazolinesSource attributionTrifluoromethyl compounds