فرمبولون

Also known as (11a,17b)-11,17-dihydroxy-17-methyl-3-oxo-Androsta-1,4-diene-2-carboxaldehyde, 11a,17b-Dihydroxy-17-methyl-3-oxo-Androsta-1,4-diene-2-carboxaldehyde, 11a,17b-Dihydroxy-17-methyl-3-oxoandrosta-1,4-diene-2-carboxaldehyde, 2-Formyl-11a-hydroxy-D1-methyltestosterone, 2-Formyl-17a-methylandrosta-1,4-dien-11a,17b-diol-3-one, 2-Formyl-17a-methylandrosta-1,4-diene-11a,17b-dihydroxy-3-one, 2-Formyl-17a-methylandrosta-1,4-diene-11a,17b-diol-3-one, 219-523-2

Formebolone (INN, BAN) (brand names Esiclene, Hubernol, Metanor), also known as formyldienolone, as well as 2-formyl-11α-hydroxy-17α-methyl-δ1-testosterone, is an orally active anabolic-androgenic steroid (AAS) described as an anticatabolic and anabolic drug that is or has been marketed in Spain and Italy. As an AAS, it shows some anabolic activity, though it is inferior to testosterone in terms of potency, but is said to have virtually no androgenic activity. Formebolone counteracts the catabolic effects (control of nitrogen balance) of potent glucocorticoids like dexamethasone phosphate. A c

Chemical data

Formula: C21H28O4
Molecular weight: 344.4 g/mol
IUPAC name: (8S,9S,10R,11R,13S,14S,17S)-11,17-dihydroxy-10,13,17-trimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-2-carbaldehyde
SMILES: C[C@@]1(CC[C@@H]2[C@@]1(C[C@H]([C@H]3[C@H]2CCC4=CC(=O)C(=C[C@]34C)C=O)O)C)O
InChIKey: AMVODTGMYSRMNP-GNIMZFFESA-N
XLogP: 2.2
Polar surface area: 74.6 Å²
H-bond donors: 2
H-bond acceptors: 4
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule

via ChEMBL · EBI

Wikidata facts

Subclass of: aldehydes
Mass: 344.198759

Show 4 more facts

chemical formula: C₂₁H₂₈O₄
isomeric SMILES: C[C@@]1(CC[C@@H]2[C@@]1(C[C@H]([C@H]3[C@H]2CCC4=CC(=O)C(=C[C@]34C)C=O)O)C)O
canonical SMILES: CC1(CCC2C1(CC(C3C2CCC4=CC(=O)C(=CC34C)C=O)O)C)O
Commons category: Formebolone

Sources (3)

via Wikidata · CC0

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via Wikidata sitelinks · CC0