Structure via PubChem · Public domain (PubChem)
foscarnet
Sign in to saveAlso known as carboxyphosphonic acid, Foscavir®, phosphonocarboxylic acid, phosphonoformic acid, phosphonomethanoic acid, Phosphonomethanoic acid, Phosphonoformic acid
Foscarnet (phosphonomethanoic acid), known by its brand name Foscavir, is an antiviral medication which is primarily used to treat viral infections involving the Herpesviridae family. It is classified as a pyrophosphate analog DNA polymerase inhibitor. Foscarnet is the conjugate base of a chemical compound with the formula HO2CPO3H2 (Trisodium phosphonoformate).
Chemical data
- Formula
- CH3O5P
- Molecular weight
- 126.01 g/mol
- IUPAC name
- phosphonoformic acid
- SMILES
- C(=O)(O)P(=O)(O)O
- InChIKey
- ZJAOAACCNHFJAH-UHFFFAOYSA-N
- XLogP
- -2
- Polar surface area
- 94.8 Ų
- H-bond donors
- 3
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Research
2,691 papers- Foscarnet-Induced Penile Ulceration.JAMA dermatology · 2023
- Clinical pharmacology: foscarnet.The American journal of medicine · 1992
- Once-Daily Foscarnet Is Effective for Human Herpesvirus 6 Reactivation after Hematopoietic Stem Cell Transplantation.Transplantation and cellular therapy · 2023
- Foscarnet-Associated Nephrogenic Diabetes Insipidus.American journal of therapeutics · 2022
- Foscarnet.Pediatrics in review · 1998
via PubMed
Wikidata facts
- Mass
- 125.972
Show 4 more facts
- chemical formula
- CH₃O₅P
- canonical SMILES
- C(=O)(O)P(=O)(O)O
- defined daily dose
- 6.5
- Commons category
- Foscarnet
via Wikidata · CC0
~3 min read
Article
7 sectionsContents
- Medical use
- Mechanism of action
- Administration
- Side effects
- References
- Sources
- External links
Foscarnet (phosphonomethanoic acid), known by its brand name Foscavir, is an antiviral medication which is primarily used to treat viral infections involving the Herpesviridae family. It is classified as a pyrophosphate analog DNA polymerase inhibitor. Foscarnet is the conjugate base of a chemical compound with the formula HO2CPO3H2 (Trisodium phosphonoformate).
Foscarnet was approved for medical use in 1991. It is available as a generic medication.