foscarnet
Also known as carboxyphosphonic acid, Foscavir®, phosphonocarboxylic acid, phosphonoformic acid, phosphonomethanoic acid, Phosphonomethanoic acid, Phosphonoformic acid
Foscarnet (phosphonomethanoic acid), known by its brand name Foscavir, is an antiviral medication which is primarily used to treat viral infections involving the Herpesviridae family. It is classified as a pyrophosphate analog DNA polymerase inhibitor. Foscarnet is the conjugate base of a chemical compound with the formula HO2CPO3H2 (Trisodium phosphonoformate).
Chemical data
- Formula
- CH3O5P
- Molecular weight
- 126.01 g/mol
- IUPAC name
- phosphonoformic acid
- SMILES
- C(=O)(O)P(=O)(O)O
- InChIKey
- ZJAOAACCNHFJAH-UHFFFAOYSA-N
- XLogP
- -2
- Polar surface area
- 94.8 Ų
- H-bond donors
- 3
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Research
2,691 papersArticle
7 sectionsContents
- Medical use
- Mechanism of action
- Administration
- Side effects
- References
- Sources
- External links
Foscarnet (phosphonomethanoic acid), known by its brand name Foscavir, is an antiviral medication which is primarily used to treat viral infections involving the Herpesviridae family. It is classified as a pyrophosphate analog DNA polymerase inhibitor. Foscarnet is the conjugate base of a chemical compound with the formula HO2CPO3H2 (Trisodium phosphonoformate).
Foscarnet was approved for medical use in 1991. It is available as a generic medication.
Connections
Categories
Anti-herpes virus drugsAntiretroviral drugsCarboxylic acidsDrugboxes which contain changes to verified fieldsDrugboxes which contain changes to watched fieldsDrugs developed by AstraZenecaMultiple chemicals in an infobox that need indexingMultiple chemicals in Infobox drugNephrotoxinsPhosphonic acids