Also known as ALKBH9, GDFD, BMIQ14, fat mass and obesity associated, FTO, alpha-ketoglutarate dependent dioxygenase
protein-coding gene in the species Homo sapiens
Gene data
FTO- Name
- FTO alpha-ketoglutarate dependent dioxygenase
- Type
- protein-coding
- Aliases
- ALKBH9, BMIQ14, GDFD, IFEX9
This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011].
via MyGene.info
Gene · Ensembl
FTO alpha-ketoglutarate dependent dioxygenase
- Symbol
- FTO
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 16:53,701,692-54,158,512
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- FTO protein.png
Show 5 more facts
- HomoloGene ID
- 8053
- exact match
- identifiers.org/ncbigene/79068
- genomic end
- 54155853
- genomic start
- 53737875
- cytogenetic location
- 16q12.2
via Wikidata · CC0
Connections
single-nucleotide polymorphism
Entity
obesity
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Q180686
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Ensembl genome database project
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human
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deoxyribonucleic acid
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enzyme
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Wikidata
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gene
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chromosome
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ribonucleic acid
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amino acid
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mitochondrion
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digital object identifier
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nucleus
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vitamin C
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hypothalamus
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Yoruba people
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allele
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body mass index
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