fumonisin
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thumb|right|400px|The chemical structure of fumonisin B1. Fumonisin refers to any one of a class of related chemical structures, the fumonisins, that constitute a group of fungal mycotoxins originally identified with genus Fusarium, a mycotoxin known for its contamination of infested corn seed (as well as other plants and foodstuffs), the infecting species, in particular, being within ''Fusarium's'' Liseola section. As shown in the example in the figure (of fumonisin B1), members of the family are composed of a central "chai[n] of about 20 carbons", and bear an "acidic ester, acetylamino and s
Research
4,457 papers- Fumonisin generation.Natural toxins · 1996
- Fumonisin B(1): Mechanisms of toxicity and biological detoxification progress in animals.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2021
- Reducing fumonisin contamination in Brazilian maize: The impact of Codex standards and regulatory frameworks.Food research international (Ottawa, Ont.) · 2024
- Research Progress on Fumonisin B1 Contamination and Toxicity: A Review.Molecules (Basel, Switzerland) · 2021
- Developmental Toxicity of Mycotoxin Fumonisin B₁ in Animal Embryogenesis: An Overview.Toxins · 2019
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- Fumonisins
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Article
4 sectionsContents
- Family background
- Mechanisms of toxicity
- Other research
- References
thumb|right|400px|The chemical structure of fumonisin B1. Fumonisin refers to any one of a class of related chemical structures, the fumonisins, that constitute a group of fungal mycotoxins originally identified with genus Fusarium, a mycotoxin known for its contamination of infested corn seed (as well as other plants and foodstuffs), the infecting species, in particular, being within ''Fusarium's Liseola section. As shown in the example in the figure (of fumonisin B1), members of the family are composed of a central "chai[n] of about 20 carbons", and bear an "acidic ester, acetylamino and sometimes other substituents". The fumonisins inhibit ceramide synthetase an enzyme that converts sphingolipids to ceramides.
==Family background== As of 2000, 15 different fumonisins had been reported, and other minor metabolites have been characterized. More specifically, the term refers primarily to the family of compounds that includes the widely studied fumonisins B1, B2, B3, and B4, as well as others. As chemical agents, the fumonisins are distinct from the large family of Fusarium trichothecene (T-2-type) mycotoxins, and from the Fusarium estrogenic metabolite, zearalenone, an F-2-type mycotoxin.