Structure via PubChem · Public domain (PubChem)
gefarnate
Sign in to saveGefarnate is a drug used for the treatment of gastric ulcers.
In the Vinony graph
Within Vinony's link graph, gefarnate is referenced by 69 other articles, and connects out to peptic ulcer disease, medication and digital object identifier.
It is catalogued under topics including Carboxylate esters, Chemical pages without DrugBank identifier and Drugboxes which contain changes to verified fields.
Its subject is documented across 7 Wikipedia language editions.
Chemical data
- Formula
- C27H44O2
- Molecular weight
- 400.6 g/mol
- IUPAC name
- [(2E)-3,7-dimethylocta-2,6-dienyl] (4E,8E)-5,9,13-trimethyltetradeca-4,8,12-trienoate
- SMILES
- CC(=CCC/C(=C/CC/C(=C/CCC(=O)OC/C=C(\C)/CCC=C(C)C)/C)/C)C
- InChIKey
- ZPACYDRSPFRDHO-ROBAGEODSA-N
- XLogP
- 9.1
- Polar surface area
- 26.3 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- gastroesophageal reflux disease, Peptic ulcer, cerebrovascular disorder, duodenal ulcer
via ChEMBL · EBI
Research
99 papers- Lipid-lowering effects of gefarnate in statin-treated patients with residual hypertriglyceridemia: a randomized controlled study.Journal of geriatric cardiology : JGC · 2024
- Gefarnate.Drug and therapeutics bulletin · 1968
- Gefarnate stimulates mucin-like glycoprotein secretion in conjunctival tissue and ameliorates corneal epithelial damage in animal dry-eye models.Clinical ophthalmology (Auckland, N.Z.) · 2013
- Gefarnate increases PAS positive cell density in rabbit conjunctiva.The British journal of ophthalmology · 1998
- Gastro-protecting effect of gefarnate on chronic erosive gastritis with dyspeptic symptoms.Chinese medical journal · 2012
via PubMed
Wikidata facts
- Mass
- 400.334
Show 4 more facts
- chemical formula
- C₂₇H₄₄O₂
- canonical SMILES
- CC(=CCCC(=CCCC(=CCCC(=O)OCC=C(C)CCC=C(C)C)C)C)C
- isomeric SMILES
- CC(=CCC/C(=C/CC/C(=C/CCC(=O)OC/C=C(\C)/CCC=C(C)C)/C)/C)C
- Commons category
- Gefarnate
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Gefarnate is a drug used for the treatment of gastric ulcers.
It also has been proposed for use in the treatment of dry eye syndrome.
Excerpted from Wikipedia’s “gefarnate” article, available under the CC BY-SA 4.0 licence.