File:Ranitidine.svg · Wikimedia Commons · See Wikimedia Commons
ranitidine
Sign in to saveAlso known as RAN
Ranitidine, sold under the brand name Zantac among others, is a medication used to decrease stomach acid production. It is used in the treatment of peptic ulcer disease, gastroesophageal reflux disease, and Zollinger–Ellison syndrome. It can be given by mouth, injection into a muscle, or injection into a vein.
Key facts
- Drug.StdInChIKey
- VMXUWOKSQNHOCA-UHFFFAOYSA-N
- Drug.image
- Ranitidine.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 250
- Drug.image2
- File:Ranitidine-A-3D-balls.png
- Drug.image_class2
- bg-transparent
- Drug.JAN
- ranitidine hydrochloride
- Drug.tradename
- Zantac, others
- Drug.MedlinePlus
- a601106
- Drug.DailyMedID
- Ranitidine
- Drug.pregnancy_AU
- B1
- Drug.routes_of_administration
- By mouth, intravenous (IV)
- Drug.class
- Histamine H2 receptor antagonist, aka H2 blocker
- Drug.ATC_prefix
- A02
- Drug.ATC_suffix
- BA02
- Drug.ATC_supplemental
- (ranitidine bismuth citrate)
- Drug.legal_AU
- S4
- Drug.legal_AU_comment
- / S2 (Pharmacy Medicine)
via Wikipedia infobox
Chemical data
- Formula
- C13H22N4O3S
- Molecular weight
- 314.41 g/mol
- IUPAC name
- 1-N'-[2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethyl]-1-N-methyl-2-nitroethene-1,1-diamine
- SMILES
- CNC(=C[N+](=O)[O-])NCCSCC1=CC=C(O1)CN(C)C
- InChIKey
- VMXUWOKSQNHOCA-UHFFFAOYSA-N
- XLogP
- 0.3
- Polar surface area
- 112 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Research
7,594 papers- Ranitidine hydrochloride.Drug intelligence & clinical pharmacy · 1983
- Ranitidine: a new H2-receptor antagonist.The New England journal of medicine · 1983
- Clinical pharmacokinetics of ranitidine.Clinical pharmacokinetics · 1984
- Ranitidine.JAMA · 1983
- N-nitrosodimethylamine (NDMA) contamination of ranitidine products: A review of recent findings.Journal of food and drug analysis · 2021
via PubMed
Wikidata facts
- Mass
- 314.141
Show 4 more facts
- chemical formula
- C₁₃H₂₂N₄O₃S
- canonical SMILES
- CNC(=C[N+](=O)[O-])NCCSCC1=CC=C(O1)CN(C)C
- Commons category
- Ranitidine
- stylized name
- raNITIdine
via Wikidata · CC0
~23 min read
Article
25 sectionsContents
- Medical uses
- Adverse effects
- Central nervous system
- Cardiovascular
- Gastrointestinal
- Liver
- Lungs
- Blood
- Skin
- Precautions
- Disease-related concerns
- Children
- Drug tests
- <span class="anchor" id="impurities"></span>Cancer-causing due to inherent instability
- List of recalls
- Pharmacology
- Mechanism of action
- Pharmacokinetics
- Elderly
- Children
- History
- Preparations
- References
- Notes
- External links
{{Infobox drug | image = Ranitidine.svg | image_class = skin-invert-image | width = 250 | alt = | image2 = File:Ranitidine-A-3D-balls.png | image_class2 = bg-transparent | alt2 = | JAN = ranitidine hydrochloride
| pronounce = | tradename = Zantac, others | Drugs.com = | MedlinePlus = a601106 | DailyMedID = Ranitidine | pregnancy_AU = B1 | pregnancy_AU_comment = | pregnancy_category = | routes_of_administration = By mouth, intravenous (IV) | class = Histamine H2 receptor antagonist, aka H2 blocker | ATC_prefix = A02 | ATC_suffix = BA02 | ATC_supplemental = (ranitidine bismuth citrate)