GHRHR
Sign in to saveAlso known as GHRFR, GRFR, IGHD1B, growth hormone releasing hormone receptor, IGHD4
protein-coding gene in the species Homo sapiens
Gene data
GHRHR- Name
- growth hormone releasing hormone receptor
- Type
- protein-coding
- Position
- 30,938,669–30,993,254 (+)
- Aliases
- GHRFR, GRFR, IGHD1B, IGHD4
- Ensembl
- ENSG00000106128
- RefSeq RNA
- NM_000823.4, NM_001009824.1
- RefSeq protein
- NP_000814.2
This gene encodes a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and release of growth hormone. Mutations in this gene have been associated with isolated growth hormone deficiency (IGHD), also known as Dwarfism of Sindh, a disorder characterized by short stature. [provided by RefSeq, Jun 2010].
Gene Ontology
Biological process
cell surface receptor signaling pathwayG protein-coupled receptor signaling pathwayadenylate cyclase-activating G protein-coupled receptor signaling pathwayadenylate cyclase-activating G protein-coupled receptor signaling pathwayadenylate cyclase-activating G protein-coupled receptor signaling pathwaypositive regulation of cell population proliferationpositive regulation of cell population proliferationpositive regulation of cell population proliferation
Molecular function
transmembrane signaling receptor activityG protein-coupled receptor activityG protein-coupled receptor activityprotein bindingG protein-coupled peptide receptor activitygrowth hormone-releasing hormone receptor activitygrowth hormone-releasing hormone receptor activitygrowth hormone-releasing hormone receptor activity
Pathways
Neuroactive ligand-receptor interaction - Homo sapiens (human)Growth hormone synthesis, secretion and action - Homo sapiens (human)Signal TransductionSignaling by GPCRClass B/2 (Secretin family receptors)GPCR downstream signallingG alpha (s) signalling eventsGlucagon-type ligand receptorsGPCR ligand bindingGPCRs, Other
via MyGene.info
Gene · Ensembl
growth hormone releasing hormone receptor
- Symbol
- GHRHR
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:30,938,669-30,993,254
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- found in taxon
- Homo sapiens
- HomoloGene ID
- 640
- exact match
- identifiers.org/ncbigene/2692
- chromosome
- human chromosome 7
- genomic start
- 30978284
- genomic end
- 31032869
- cytogenetic location
- 7p14.3
- expressed in
- nucleus accumbens
via Wikidata · CC0