GLRX5
Sign in to saveAlso known as C14orf87, FLB4739, GRX5, PR01238, PRO1238, PRSA, SIDBA3, SPAHGC
Glutaredoxin 5, also known as GLRX5, is a protein which in humans is encoded by the GLRX5 gene located on chromosome 14. This gene encodes a mitochondrial protein, which is evolutionarily conserved. It is involved in the biogenesis of iron- sulfur clusters, which are required for normal iron homeostasis. Mutations in this gene are associated with autosomal recessive pyridoxine-refractory sideroblastic anemia.
Gene data
GLRX5- Name
- glutaredoxin 5
- Type
- protein-coding
- Aliases
- C14orf87, FLB4739, GRX5, PR01238, PRO1238, PRSA, SIDBA3, SPAHGC
This gene encodes a mitochondrial protein, which is evolutionarily conserved. It is involved in the biogenesis of iron-sulfur clusters, which are required for normal iron homeostasis. Mutations in this gene are associated with autosomal recessive pyridoxine-refractory sideroblastic anemia. [provided by RefSeq, May 2010].
via MyGene.info
Gene · Ensembl
glutaredoxin 5
- Symbol
- GLRX5
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 14:95,533,503-95,544,724
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 31984
- exact match
- identifiers.org/ncbigene/51218
- genomic end
- 96011061
- genomic start
- 95999840
- cytogenetic location
- 14q32.13
Sources (6)
via Wikidata · CC0
~2 min read
Article
6 sectionsContents
- Structure
- Function
- Clinical significance
- See also
- References
- Further reading
Glutaredoxin 5, also known as GLRX5, is a protein which in humans is encoded by the GLRX5 gene located on chromosome 14. This gene encodes a mitochondrial protein, which is evolutionarily conserved. It is involved in the biogenesis of iron- sulfur clusters, which are required for normal iron homeostasis. Mutations in this gene are associated with autosomal recessive pyridoxine-refractory sideroblastic anemia.
== Structure ==