GMDS
Sign in to saveAlso known as GMD, SDR3E1, GDP-mannose 4,6-dehydratase
protein-coding gene in the species Homo sapiens
Gene data
GMDS- Name
- GDP-mannose 4,6-dehydratase
- Type
- protein-coding
- Aliases
- GMD, SDR3E1
GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).[supplied by OMIM, Aug 2009].
via MyGene.info
Gene · Ensembl
GDP-mannose 4,6-dehydratase
- Symbol
- GMDS
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:1,622,884-2,245,711
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein GMDS PDB 1t2a.png
Show 5 more facts
- HomoloGene ID
- 75968
- cytogenetic location
- 6p25.3
- exact match
- identifiers.org/ncbigene/2762
- genomic end
- 2245605
- genomic start
- 1624041
via Wikidata · CC0
Connections
Q180686
Entity
human chromosome 6
Entity
Ensembl genome database project
Entity
human
Entity
enzyme
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Wikidata
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gene
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chromosome
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digital object identifier
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bibcode
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human genome
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Q229883
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base pair
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locus
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gene expression
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mannose
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Online Mendelian Inheritance in Man
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Protein Data Bank
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Q22908627
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Entrez
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