Image by SONVU9491 on Pixabay · Pixabay License
Also known as ARSC, ARSC2, ARSC1, ASC, ES, SSDD, XLI, Steroid sulfatase (microsomal), isozyme S
protein-coding gene in the species Homo sapiens
Gene data
STS- Name
- steroid sulfatase
- Type
- protein-coding
- Chromosome
- X
- Aliases
- ARSC, ARSC1, ASC, ES, SSDD, XLI
This gene encodes a multi-pass membrane protein that is localized to the endoplasmic reticulum. It belongs to the sulfatase family and hydrolyzes several 3-beta-hydroxysteroid sulfates, which serve as metabolic precursors for estrogens, androgens, and cholesterol. Mutations in this gene are associated with X-linked ichthyosis (XLI). Alternatively spliced transcript variants resulting from the use of different promoters have been described for this gene (PMID:17601726). [provided by RefSeq, Mar 2016].
via MyGene.info
Gene · Ensembl
steroid sulfatase
- Symbol
- STS
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr X:7,147,237-7,804,358
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein STS PDB 1p49.png
Show 5 more facts
- HomoloGene ID
- 47918
- exact match
- identifiers.org/ncbigene/412
- genomic end
- 7804358
- genomic start
- 7147237
- cytogenetic location
- Xp22.31
via Wikidata · CC0