Image by SONVU9491 on Pixabay · Pixabay License
Also known as ARSC, ARSC2, ARSC1, ASC, ES, SSDD, XLI, Steroid sulfatase (microsomal), isozyme S
gene da espécie Homo sapiens
In the Vinony graph
Within Vinony's link graph, STS is referenced by 548 other articles, and connects out to steroid, enzyme and PubMed.
It is catalogued under topics including EC 3.1.6, Endocrinology and Genes on human chromosome X.
Its subject is documented across 7 Wikipedia language editions.
Gene data
STS- Name
- steroid sulfatase
- Type
- protein-coding
- Chromosome
- X
- Aliases
- ARSC, ARSC1, ASC, ES, SSDD, XLI
This gene encodes a multi-pass membrane protein that is localized to the endoplasmic reticulum. It belongs to the sulfatase family and hydrolyzes several 3-beta-hydroxysteroid sulfates, which serve as metabolic precursors for estrogens, androgens, and cholesterol. Mutations in this gene are associated with X-linked ichthyosis (XLI). Alternatively spliced transcript variants resulting from the use of different promoters have been described for this gene (PMID:17601726). [provided by RefSeq, Mar 2016].
via MyGene.info
Gene · Ensembl
steroid sulfatase
- Symbol
- STS
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr X:7,147,237-7,804,358
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein STS PDB 1p49.png
Show 8 more facts
- HomoloGene ID
- 47918
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/412
- chromosome
- human X chromosome
- genomic end
- 7804358
- genomic start
- 7147237
- cytogenetic location
- Xp22.31
- expressed in
- Brodmann area 46
via Wikidata · CC0