Also known as IAP, alkaline phosphatase, intestinal
Alkaline phosphatase, intestinal, also known as ALPI, is a type of alkaline phosphatase that in humans is encoded by the ALPI gene. Its chemical formula is:C2679H4196O965N672S18P2.
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The intestinal alkaline phosphatase gene encodes a digestive brush-border enzyme. This enzyme is a component of the gut mucosal defense system and is thought to function in the detoxification of lipopolysaccharide, and in the prevention of bacterial translocation in the gut. [provided by RefSeq, Dec 2014].
via MyGene.info
Alkaline phosphatase, intestinal, also known as ALPI, is a type of alkaline phosphatase that in humans is encoded by the ALPI gene. Its chemical formula is:C2679H4196O965N672S18P2.
Intestinal alkaline phosphatase is an endogenous enzyme that maintains gut homeostasis. It detoxifyies bacterial toxins, dephosphorylates phosphorylated nucleotides, regulates lipid absorption in the intestine, and regulates the microbiome in the intestine. In addition to these functions, intestinal alkaline phosphatase can also modulate bicarbonate secretion and can modulate the pH of the duodenum.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).