Lipase C, hepatic type
Sign in to saveAlso known as lipase member C, lipase, hepatic, hepatic triacylglycerol lipase, LIPC, hepatic lipase, Triacylglycerol lipase
mammalian protein found in Homo sapiens
In the Vinony graph
Within Vinony's link graph, Lipase C, hepatic type is referenced by 509 other articles, and connects out to triglyceride, PubMed and Ensembl genome database project.
It is catalogued under topics including Enzymes, Genes on human chromosome 15 and Peripheral membrane proteins.
Its subject is documented across 10 Wikipedia language editions.
Protein · UniProt
Hepatic triacylglycerol lipase
- Gene
- LIPC
- Organism
- Homo sapiens (Human)
- Length
- 499 aa
- Molecular mass
- 55,914 Da
- Evidence
- 1: Evidence at protein level
Catalyzes the hydrolysis of triglycerides and phospholipids present in circulating plasma lipoproteins, including chylomicrons, intermediate density lipoproteins (IDL), low density lipoproteins (LDL) of large size and high density lipoproteins (HDL), releasing free fatty acids (FFA) and smaller lipoprotein particles (PubMed:12032167, PubMed:26193433, PubMed:7592706, PubMed:8798474). Also exhibits lysophospholipase activity (By similarity). Can hydrolyze both neutral lipid and phospholipid substrates but shows a greater binding affinity for neutral lipid substrates than phospholipid substrat…
Swiss-Prot (reviewed) · via UniProt
Clinical Trials
1 registered- NACOMPLETEDDietary Modulation of Hepatic Lipase (LIPC) -514 C/T Variant Associations With Lipids and GlucoseTufts University · NCT02938091
Wikidata facts
- Instance of
- protein
- Image
- LIPC protein.png
Show 3 more facts
- found in taxon
- Homo sapiens
- cell component
- extracellular space
- Commons category
- Hepatic lipase
via Wikidata · CC0