UCHL1
Sign in to saveAlso known as HEL-117, NDGOA, PARK5, PGP 9.5, PGP9.5, PGP95, Uch-L1, HEL-S-53
protein-coding gene in the species Homo sapiens
Gene data
UCHL1- Name
- ubiquitin C-terminal hydrolase L1
- Type
- protein-coding
- Position
- 41,256,413–41,268,560 (+)
- Aliases
- HEL-117, HEL-S-53, NDGOA, PARK5, PGP 9.5, PGP9.5, PGP95, SPG79, SPG79A, UCHL-1
- Ensembl
- ENSG00000154277
- RefSeq RNA
- NM_004181.5
- RefSeq protein
- NP_004172.2
The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.[provided by RefSeq, Sep 2009].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
ubiquitin C-terminal hydrolase L1
- Symbol
- UCHL1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:41,256,413-41,268,567
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein UCHL1 PDB 2etl.png
Show 5 more facts
- HomoloGene ID
- 37894
- exact match
- identifiers.org/ncbigene/7345
- genomic end
- 41270472
- genomic start
- 41258430
- cytogenetic location
- 4p13
Sources (4)
via Wikidata · CC0
Available in 11 languages
via Wikidata sitelinks · CC0
Connections
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