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PETase
EntityQ25384423· pop 12· linked from 459 articles

PETases are an esterase class of enzymes that catalyze the breakdown (via hydrolysis) of polyethylene terephthalate (PET) plastic to monomeric mono-2-hydroxyethyl terephthalate (MHET).

Key facts

Enzyme.name
PETase
Enzyme.AltNames
PET hydrolase, poly(ethylene terephthalate) hydrolase
Enzyme.image
PETase_5XH3_with_HEMT-cartoon.png
Enzyme.caption
I. sakaiensis PETase () in complex with HEMT, a PET analogue ().
Enzyme.EC_number
3.1.1.101

via Wikipedia infobox

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Article

6 sections
Contents
  • History
  • Structure
  • Mutations
  • Biological pathway {{anchor|MHET breakdown in I. sakaiensis}}
  • See also
  • References

PETases are an esterase class of enzymes that catalyze the breakdown (via hydrolysis) of polyethylene terephthalate (PET) plastic to monomeric mono-2-hydroxyethyl terephthalate (MHET).

The idealized chemical reaction is: (ethylene terephthalate)n + H2O → (ethylene terephthalate)n-1 + MHET, where n is the number of monomers in the polymer chain, though a trace amount of the PET breaks down instead to bis(2-hydroxyethyl) terephthalate (BHET). PETases can also break down PEF-plastic (polyethylene-2,5-furandicarboxylate), which is a bioderived PET replacement, into the analogous . PETases can't catalyze the hydrolysis of aliphatic polyesters like polybutylene succinate or polylactic acid.

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