hand, foot and mouth disease
Also known as Vesicular stomatitis and exanthem, HFMD, Hand Foot and Mouth Disease, Hand, Foot, and Mouth Disease
human disease
AI overview
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Research
4,059 papers- Hand-Foot-and-Mouth Disease: Rapid Evidence Review.ReviewAmerican family physician · 2019Saguil A, Kane SF, Lauters R et al.
- Hand, foot and mouth disease: current knowledge on clinical manifestations, epidemiology, aetiology and prevention.ReviewEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2018Esposito S, Principi NDOI: 10.1007/s10096-018-3206-x
- A review of enterovirus-associated hand-foot and mouth disease: preventive strategies and the need for a global enterovirus surveillance network.ReviewPathogens and global health · 2024Huang CY, Su SB, Chen KTDOI: 10.1080/20477724.2024.2400424
- Hand-foot-and-mouth disease caused by coxsackievirus A6 on the rise.Review
~12 min read
Article
Hand, foot, and mouth disease (HFMD) is a common infection caused by a group of enteroviruses. It typically begins with a fever and feeling generally unwell. This is followed a day or two later by flat discolored spots or bumps that may blister, on the hands, feet and mouth and occasionally buttocks and groin. Signs and symptoms normally appear 3–6 days after exposure to the virus. The rash generally resolves on its own in about a week.
The viruses that cause HFMD are spread through close personal contact, through the air from coughing, and via the feces of an infected person. Contaminated objects can also spread the disease. Coxsackievirus A16 is the most common cause, and enterovirus 71 is the second-most common cause. Other strains of coxsackievirus and enterovirus can also be responsible. Some people may carry and pass on the virus despite having no symptoms of disease. No animals are involved in transmission. Diagnosis can often be made based on symptoms. Occasionally, a throat or stool sample may be tested for the virus.