hepatotoxicity
Sign in to saveAlso known as liver damage, toxic hepatitis, chemical or drug-induced liver injury, Chemical and Drug Induced Liver Injury
{| class="infobox" style="font-size: 88%; text-align: center; width: 22em; line-height: 1.5em" ! Synonyms |- | Drug-induced liver injury (DILI) Toxin-induced hepatitis Drug-induced hepatitis Drug-induced hepatic necrosis Drug-induced hepatic fibrosis Drug-induced hepatic granuloma Toxic liver disease with hepatitis Toxic liver disease with cholestasisToxic hepatitis Toxic liver diseaseToxin-induced liver diseaseDrug-induced liver diseaseDrug-induced liver damageHepatogenous poisoning |}
Key facts
- Medical condition (new).synonyms
- see below list
- Medical condition (new).image
- Drug-induced hepatitis low mag.jpg
- Medical condition (new).caption
- Drug-induced hepatitis with granulomata. Other causes were excluded with extensive investigations. Liver biopsy. H&E stain.
- Medical condition (new).field
- Gastroenterology, Toxicology
- Medical condition (new).complications
- Cirrhosis, liver failure
via Wikipedia infobox
Research
35,393 papers- Hepatotoxicity induced by nanomaterials: mechanisms and in vitro models.Archives of toxicology · 2021
- Hepatotoxicity due to dietary supplements: state-of-the-art, gaps and perspectives.Critical reviews in toxicology · 2023
- Metabolism and Hepatotoxicity of Pyrazinamide, an Antituberculosis Drug.Drug metabolism and disposition: the biological fate of chemicals · 2021
- Possible Pathways of Hepatotoxicity Caused by Chemical Agents.Current drug metabolism · 2019
- [Once upon a time the hepatotoxicity…].Medecine sciences : M/S · 2021
via PubMed
~20 min read
Encyclopedic overview
26 sectionsContents
- Causes
- Paracetamol
- Nonsteroidal anti-inflammatory drugs
- Glucocorticoids
- Isoniazid
- Other hydrazine derivative drugs
- Natural products
- Alternative remedies
- Industrial toxin
- Mechanism
- Drug metabolism in liver
- Patterns of injury
- Zonal necrosis
- Hepatitis
- Cholestasis
- Steatosis
- Granuloma
- Vascular lesions
- Neoplasm
- Diagnosis
- Treatment
- Prognosis
- Drugs withdrawn
- See also
- References
- External links
{| class="infobox" style="font-size: 88%; text-align: center; width: 22em; line-height: 1.5em" ! Synonyms |- | Drug-induced liver injury (DILI) Toxin-induced hepatitis Drug-induced hepatitis Drug-induced hepatic necrosis Drug-induced hepatic fibrosis Drug-induced hepatic granuloma Toxic liver disease with hepatitis Toxic liver disease with cholestasisToxic hepatitis Toxic liver diseaseToxin-induced liver diseaseDrug-induced liver diseaseDrug-induced liver damageHepatogenous poisoning |}
Hepatotoxicity refers to chemical-driven liver damage. Drug-induced liver injury (DILI) is a cause of acute and chronic liver disease caused specifically by medications and the most common reason for a drug to be withdrawn from the market after approval.
Excerpted from Wikipedia’s “hepatotoxicity” article, available under the CC BY-SA 4.0 licence.