HEPN1

Also known as hepatocellular carcinoma, down-regulated 1

Hepatocellular carcinoma, down-regulated 1 is a protein that in humans is encoded by the HEPN1 gene.

In the Vinony graph

Within Vinony's link graph, HEPN1 is referenced by 2 other articles, and connects out to PubMed, human chromosome 11 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 11.

Its subject is documented across 5 Wikipedia language editions.

Gene data

HEPN1

Name: hepatocellular carcinoma, down-regulated 1
Type: protein-coding
Position: 124,919,250–124,920,677 (+)
Ensembl: ENSG00000221932
RefSeq RNA: NM_001037558.4, NR_170124.1
RefSeq protein: NP_001032647.2

This gene is expressed predominantly in the liver. Transient transfection studies show the expression of this gene significantly inhibits cell growth, suggesting a role for this gene in apoptosis. Expression of this gene is down-regulated or lost in hepatocellular carcinomas (HCC), suggesting that loss of this gene is involved in carcinogenesis of hepatocytes (PMID:12971969). This gene maps to the 3'-noncoding region of the HEPACAM gene (GeneID:220296) on the antisense strand. [provided by RefSeq, Aug 2020].