CDK5RAP1
Sign in to saveAlso known as C20orf34, C42, CGI-05, HSPC167, CDK5 regulatory subunit associated protein 1
CDK5 regulatory subunit-associated protein 1 is a protein that in humans is encoded by the CDK5RAP1 gene.
In the Vinony graph
Within Vinony's link graph, CDK5RAP1 is referenced by 2 other articles, and connects out to PubMed, human chromosome 20 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 20.
Its subject is documented across 5 Wikipedia language editions.
Gene data
CDK5RAP1- Name
- CDK5RAP1 mitochondrial tRNA methylthiotransferase
- Type
- protein-coding
- Position
- 33,348,588–33,401,561 (−)
- Aliases
- C20orf34, C42, CGI-05, HSPC167
- Ensembl
- ENSG00000101391
- RefSeq RNA
- NM_001278167.2, NM_001278168.2, NM_001278169.1, NM_001365728.1, NM_016082.4
- RefSeq protein
- NP_001265096.1, NP_001265097.1, NP_001265098.1, NP_001352657.1, NP_057166.4
This gene encodes a regulator of cyclin-dependent kinase 5 activity. This protein has also been reported to modify RNA by adding a methylthio-group and may thus have a dual function as an RNA methylthiotransferase and as an inhibitor of cyclin-dependent kinase 5 activity. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
CDK5RAP1 mitochondrial tRNA methylthiotransferase
- Symbol
- CDK5RAP1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:33,348,588-33,401,561
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 9502
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/51654
- genomic end
- 31989367
- genomic start
- 31946645
- chromosome
- human chromosome 20
- cytogenetic location
- 20q11.21
- expressed in
- spleen
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
CDK5 regulatory subunit-associated protein 1 is a protein that in humans is encoded by the CDK5RAP1 gene.
Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. Multiple transcript variants exist for this gene, but the full-length natures of only two have been determined.
Excerpted from Wikipedia’s “CDK5RAP1” article, available under the CC BY-SA 4.0 licence.