CDK5RAP1

Also known as C20orf34, C42, CGI-05, HSPC167, CDK5 regulatory subunit associated protein 1

CDK5 regulatory subunit-associated protein 1 is a protein that in humans is encoded by the CDK5RAP1 gene.

Gene data

CDK5RAP1

Name: CDK5RAP1 mitochondrial tRNA methylthiotransferase
Type: protein-coding
Aliases: C20orf34, C42, CGI-05, HSPC167

This gene encodes a regulator of cyclin-dependent kinase 5 activity. This protein has also been reported to modify RNA by adding a methylthio-group and may thus have a dual function as an RNA methylthiotransferase and as an inhibitor of cyclin-dependent kinase 5 activity. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013].

via MyGene.info

Gene · Ensembl

CDK5RAP1 mitochondrial tRNA methylthiotransferase

Symbol: CDK5RAP1
Biotype: Protein coding
Organism: Homo sapiens
Location: 20:33,348,588-33,401,561
Strand: Reverse (−)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

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HomoloGene ID: 9502
exact match: identifiers.org/ncbigene/51654
genomic end: 31989367
genomic start: 31946645
cytogenetic location: 20q11.21

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CDK5 regulatory subunit-associated protein 1 is a protein that in humans is encoded by the CDK5RAP1 gene.

Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. Multiple transcript variants exist for this gene, but the full-length natures of only two have been determined.