CDK5RAP3

Also known as C53, HSF-27, IC53, LZAP, MST016, OK/SW-cl.114, PP1553, CDK5 regulatory subunit associated protein 3

CDK5 regulatory subunit-associated protein 3 is a protein that in humans is encoded by the CDK5RAP3 gene.

In the Vinony graph

Vinony's link graph records 3 inbound references to CDK5RAP3, and connects out to PubMed, human chromosome 17 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 17.

Vinony links it to 5 Wikipedia language editions.

Gene data

CDK5RAP3

Name: CDK5 regulatory subunit associated protein 3
Type: protein-coding
Position: 47,967,810–47,981,787 (+)
Aliases: C53, HSF-27, IC53, LZAP, MST016, OK/SW-cl.114, PP1553
Ensembl: ENSG00000108465
RefSeq RNA: NM_001278197.2, NM_001278198.2, NM_001278216.2, NM_001278217.2, NM_025197.2
RefSeq protein: NP_001265126.1, NP_001265127.1, NP_001265145.1, NP_001265146.1, NP_788276.1

This gene encodes a protein that has been reported to function in signaling pathways governing transcriptional regulation and cell cycle progression. It may play a role in tumorigenesis and metastasis. A pseudogene of this gene is located on the long arm of chromosome 20. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013].

via MyGene.info

Gene · Ensembl

CDK5 regulatory subunit associated protein 3

Symbol: CDK5RAP3
Biotype: Protein coding
Organism: Homo sapiens
Location: 17:47,967,810-47,981,787
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 7 more facts

HomoloGene ID: 12718
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/80279
genomic end: 47981781
genomic start: 46045176
chromosome: human chromosome 17
cytogenetic location: 17q21.32

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

3 sections

Contents

References
Further reading
External links

CDK5 regulatory subunit-associated protein 3 is a protein that in humans is encoded by the CDK5RAP3 gene.

Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. The encoded protein, which may be a substrate of neuronal CDC2-like kinase, has also been found in vascular endothelial cells, where it mediates cell proliferation.

Excerpted from Wikipedia’s “CDK5RAP3” article, available under the CC BY-SA 4.0 licence.