PICK1
Sign in to saveAlso known as PICK, PRKCABP, protein interacting with PRKCA 1
Protein Interacting with C Kinase - 1 is a protein that in humans is encoded by the PICK1 gene.
Gene data
PICK1- Name
- protein interacting with PRKCA 1
- Type
- protein-coding
- Aliases
- PICK, PRKCABP
The protein encoded by this gene contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
protein interacting with PRKCA 1
- Symbol
- PICK1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 22:38,056,311-38,076,050
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein PICK1 PDB 2gzv.png
Show 5 more facts
- HomoloGene ID
- 7470
- exact match
- identifiers.org/ncbigene/9463
- genomic end
- 38471708
- genomic start
- 38452318
- cytogenetic location
- 22q13.1
Sources (4)
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Function
- Interactions
- References
- Further reading
- External links
Protein Interacting with C Kinase - 1 is a protein that in humans is encoded by the PICK1 gene.
== Function ==