MAP2K1

Name

mitogen-activated protein kinase kinase 1

Type

protein-coding

Position

66,386,825–66,491,656 (+)

Aliases

CFC3, MAPKK1, MEK1, MEL, MKK1, PRKMK1

Ensembl

ENSG00000169032

RefSeq RNA

NM_001411065.1, NM_002755.4, XM_011521783.4, XM_017022411.3, XM_054378443.1

RefSeq protein

NP_001397994.1, NP_002746.1, XP_011520085.1, XP_016877900.1, XP_054234418.1

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

mitogen-activated protein kinase kinase 1

Symbol

MAP2K1

Biotype

Protein coding

Organism

Homo sapiens

Location

15:66,386,816-66,491,656

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Image

Protein MAP2K1 PDB 1s9j.png

via Wikidata · CC0