MAP3K10
Sign in to saveAlso known as MEKK10, MLK2, MST, mitogen-activated protein kinase kinase kinase 10
Mitogen-activated protein kinase kinase kinase 10 is an enzyme that in humans is encoded by the MAP3K10 gene.
Gene data
MAP3K10- Name
- mitogen-activated protein kinase kinase kinase 10
- Type
- protein-coding
- Position
- 40,191,426–40,215,578 (+)
- Aliases
- MEKK10, MLK2, MST
- Ensembl
- ENSG00000130758
- RefSeq RNA
- NM_002446.4, XM_011526981.3, XM_011526982.4, XM_047438844.1, XM_047438845.1
- RefSeq protein
- NP_002437.2, XP_011525283.1, XP_011525284.1, XP_047294800.1, XP_047294801.1
The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
mitogen-activated protein kinase kinase kinase 10
- Symbol
- MAP3K10
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 19:40,191,412-40,215,579
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 1834
- exact match
- identifiers.org/ncbigene/4294
- genomic end
- 40721482
- genomic start
- 40191426
- cytogenetic location
- 19q13.2
Sources (3)
via Wikidata · CC0
~1 min read
Article
4 sectionsContents
- Function
- Interactions
- References
- Further reading
Mitogen-activated protein kinase kinase kinase 10 is an enzyme that in humans is encoded by the MAP3K10 gene.
== Function ==