MKNK1
Sign in to saveAlso known as MNK1, MAP kinase interacting serine/threonine kinase 1, MAPK interacting serine/threonine kinase 1
MAP kinase-interacting serine/threonine-protein kinase 1 is an enzyme that in humans is encoded by the MKNK1 gene.
Gene data
MKNK1- Name
- MAPK interacting serine/threonine kinase 1
- Type
- protein-coding
- Position
- 46,557,407–46,616,850 (−)
- Aliases
- MNK1
- Ensembl
- ENSG00000079277
- RefSeq RNA
- NM_001135553.4, NM_001377337.1, NM_001377338.1, NM_001377341.1, NM_001377342.1
- RefSeq protein
- NP_001129025.2, NP_001364266.1, NP_001364267.1, NP_001364270.1, NP_001364271.1
This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
MAPK interacting serine/threonine kinase 1
- Symbol
- MKNK1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:46,557,407-46,616,850
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
3 sectionsContents
- Interactions
- References
- Further reading
MAP kinase-interacting serine/threonine-protein kinase 1 is an enzyme that in humans is encoded by the MKNK1 gene.
==Interactions== MKNK1 has been shown to interact with MAPK1 and Eukaryotic translation initiation factor 4 gamma.
Excerpted from Wikipedia’s “MKNK1” article, available under the CC BY-SA 4.0 licence.