HM13
Sign in to saveAlso known as H13, IMP1, IMPAS, IMPAS-1, MSTP086, PSENL3, PSL3, SPP
Minor histocompatibility antigen H13 is a protein that in humans is encoded by the HM13 gene.
Gene data
HM13- Name
- histocompatibility minor 13
- Type
- protein-coding
- Aliases
- H13, HM13-IT1, IMP1, IMPAS, IMPAS-1, MSTP086, PSENL3, PSL3, SPP, SPPL1
The protein encoded by this gene, which localizes to the endoplasmic reticulum, catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein. This activity is required to generate signal sequence-derived human lymphocyte antigen-E epitopes that are recognized by the immune system, and to process hepatitis C virus core protein. The encoded protein is an integral membrane protein with sequence motifs characteristic of the presenilin-type aspartic proteases. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
histocompatibility minor 13
- Symbol
- HM13
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:31,514,370-31,577,923
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 7749
- exact match
- identifiers.org/ncbigene/81502
- genomic end
- 30157370
- genomic start
- 31514410
- cytogenetic location
- 20q11.21
Sources (4)
via Wikidata · CC0
~2 min read
Article
3 sectionsContents
- Function
- References
- Further reading
Minor histocompatibility antigen H13 is a protein that in humans is encoded by the HM13 gene.
== Function ==